Featured Review Articles
(work led or co-led by our lab)
2026
(opens in new tab) Qiu, Shendure. Remembrance of inflammations past
(opens in new tab) Nathans, McDiarmid et al. Multichannel genomic recording of biological information with ENGRAM
2024
(opens in new tab) Askary et al. The lives of cells, recorded
(opens in new tab) Liao, Choi, Shendure. Molecular recording using DNA Typewriter
(opens in new tab) Nathans et al. Genetic Tools for Cell Lineage Tracing and Profiling Developmental Trajectories in the Skin
2023
(opens in new tab) Domcke, Shendure. A reference cell tree will serve science better than a reference cell atlas
2022
(opens in new tab) Boeckh et al. The Seattle Flu Study: when regulations hinder pandemic surveillance
2021
(opens in new tab) Qiu, Shendure. A continuous model of early mammalian development
2020
(opens in new tab) Gordon, Inoue, Martin, Schubach et al. lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements
(opens in new tab) Gasperini, Tome, Shendure. Towards a comprehensive catalogue of validated and target-linked human enhancers
2019
(opens in new tab) Kim et al. Mechanisms of Interplay between Transcription Factors and the 3D Genome
(opens in new tab) Shendure et al. Genomic Medicine-Progress, Pitfalls, and Promise
2018
(opens in new tab) Klein et al. Identifying Novel Enhancer Elements with CRISPR-Based Screens
2017
(opens in new tab) Shendure et al. DNA sequencing at 40: past, present and future
(opens in new tab) Starita et al. Variant Interpretation: Functional Assays to the Rescue
2016
(opens in new tab) Shendure. Human genomics: A deep dive into genetic variation
(opens in new tab) Fields, Shendure. Massively Parallel Genetics
(opens in new tab) Gasperini et al. The power of multiplexed functional analysis of genetic variants
2015
(opens in new tab) Snyder et al. Haplotype-resolved genome sequencing: experimental methods and applications
(opens in new tab) Kircher, Shendure. Running spell-check to identify regulatory variants
(opens in new tab) Shendure, Akey. The origins, determinants, and consequences of human mutations
2014
(opens in new tab) Shendure. Life after genetics
(opens in new tab) Kumar et al. Genome sequencing of idiopathic pulmonary fibrosis in conjunction with a medical school human anatomy course
2013
(opens in new tab) Shendure. 2012 Curt Stern Award address
(opens in new tab) Snyder et al. Noninvasive fetal genome sequencing: a primer
2012
(opens in new tab) Kohane, Shendure. What's a Genome Worth? Science Translational Medicine (2012)
(opens in new tab) Shendure, Lieberman-Aiden. The expanding scope of DNA sequencing
2011
(opens in new tab) Shendure. Next-generation human genetics
(opens in new tab) Cooper, Shendure. Needles in stacks of needles: finding disease-causal variants in a wealth of genomic data
(opens in new tab) Bamshad et al. Exome sequencing as a tool for Mendelian disease gene discovery
2010
(opens in new tab) Ng et al. Massively parallel sequencing and rare disease
(opens in new tab) Mamanova et al. Target-enrichment strategies for next-generation sequencing
2009
(opens in new tab) Turner et al. Methods for genomic partitioning
2008
(opens in new tab) Shendure. The beginning of the end for microarrays? Nature Methods (2008)
(opens in new tab) Shendure, Ji. Next generation DNA sequencing
2004
(opens in new tab) Shendure et al. Advanced sequencing technologies: methods and goals